Thermodynamic investigation of micellization of zwitterionic detergent CHAPS: temperature, salt and pH dependence
نویسندگان
چکیده
The zwitterionic detergent 3-[(3-cholamidopropyl)-dimethylammonium]-1-propanesulfonate (CHAPS), derivative of naturally occurring bile salts, is widely used in biochemistry for membrane protein and receptor solubilization and purification. Since the efficiency of protein stabilization is known to be highly related to the detergent concentration, it is very important for the researcher to predict the best non-denaturing conditions [1].
منابع مشابه
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